徐琳
一、学术简历
【学习经历】
香港大学:公共卫生学、流行病学双硕士学位、流行病学博士学位
中山大学:医学学士学位
【工作经历】
2016~至今 中山大学 公共卫生学院 教授、博士生导师
2024~至今 香港大学 荣誉教授,博士生联合导师
2022~至今 英国伯明翰大学 荣誉高级研究员
2021~2023 香港大学 荣誉副教授,博士生联合导师
2015~2020 香港大学 研究助理教授,博士生联合导师
2012~2015 香港大学 公共卫生学院 博士后
二、社会兼职
国际流行病学期刊(IJE)编委
中华预防医学会流行病学分会青年委员会委员
广东省预防医学会流行病学专业委员会委员
广东省营养学会营养与慢病管理专业委员会委员
广东省康复医学会脑卒中康复专业委员会副主任委员
担任了多份重要国际医学期刊的审稿人,包括 Nature, Nature Communication, Lancet Diabetes & Endocrinology, BMJ, JAMA, Nature medicine等等。
三、主要承担或参与的课题
1. 国家自然科学基金面上项目,82373661,ANGPTLs基因及其蛋白表达水平调控内脏脂肪组织影响健康衰老表型的前瞻性队列研究,2024/01~2027/12,49万元,主持
2. 国家自然科学基金(“长寿重要相关因素及其作用机制研究”专项项目),81941019,基于遗传和环境多维度构建和验证健康衰老表型预测模型的队列研究,2020/01~2022/12,90万元,已结题,主持
3. 国家“十三五”科技重大专项课题(增补课题),2018ZX10715004-003-003,乙肝及肝癌诊断及监测新型血清标记物在慢性HBV患者中的推广应用研究,2019/01-2020/12,211.01万元,已结题,(增补课题)负责人
4. 广东省自然科学基金,2018A030313140,血睾酮与缺血性心脏病:结合孟德尔随机化分析的人群前瞻性队列研究,2018/01-2020/12,10万,结题,主持
5. 香港健康医学研究基金(HMRF),13143241,A prospective study of Southern Chinese dietary pattern, foods and nutrients with cardiovascular disease mortality(中文题目:南中国膳食模式、食物及营养素对心血管疾病及死亡的前瞻性队列研究,2016/04-2017/03, 53万港币,已结题,主持
6. 香港大学研究资助基金,201510159006,Establishment of cardiovascular risk prediction score in middle-age to older Chinese people(中文题目:建立中老年人心血管疾病的预测公式),2016/01-2016/12, 15.0万港币,已结题,主持
7. 香港健康医学研究基金(HMRF),12133631,Do common liver virus infections(HAV, HBV and HCV) contribute to high diabetes risk in China?(中文题目:常见肝病毒感染是否可引起中国高糖尿病患病率?),2014/04-2015/03, 70.1万港币,已结题,主持
8. 香港大学研究资助基金,201309176086, Progression of carotid intima-media thickness and related cardiovascular outcomes in older Chinese people (中文题目:颈脉内膜-中层厚度的进展对心血管事件发生的影响),2014/01-2014/12, 5.23万港币,已结题,主持
四、近期发表的主要文章:近10年以第一/通讯作者发表SCI论文超过90篇。部分代表性论著如下:
(1). Wang J, Li YR, Jiang CQ, Zhang WS, Zhu T, Zhu F, Jin YL, Lam TH, Cheng KK, Xu L(*). Chronotype and cognitive function: Observational study and bidirectional Mendelian randomization. eClinicalMedicine 2022:101713 doi: https://doi.org/10.1016/j.eclinm.2022.101713
(2). Wang J, Zhang WS(*), Jiang CQ, Zhu F, Jin YL, Cheng KK, Lam TH, Xu L(*): Associations of face-to-face and non-face-to-face social isolation with all-cause and cause-specific mortality: 13-year follow-up of the Guangzhou Biobank Cohort study. BMC Med 2022, 20(1):178.
(3). Tian WB, Zhang WS, Jiang CQ, Liu XY, Jin YL, Lam TH, Cheng KK, Xu L(*): Aortic arch calcification and risk of all-cause mortality and cardiovascular disease: The Guangzhou Biobank Cohort Study. The Lancet regional health Western Pacific 2022, 23:100460.
(4). Li MJ, Ren J, Zhang WS, Jiang CQ, Jin YL, Lam TH, Cheng KK, Thomas GN, Xu L(*): Association of alcohol drinking with incident type 2 diabetes and pre-diabetes: The Guangzhou Biobank Cohort Study. Diabetes Metab Res Rev 2022:e3548.
(5). Sun C (#), Li K (#), Xu H (#), Wang X, Qin P, Wang S, Liang B(*), Xu L(*). Association of healthy lifestyle score with all-cause mortality and life expectancy: a city-wide prospective cohort study of cancer survivors. BMC Med. 2021 Jul 7;19(1):158. doi: 10.1186/s12916-021-02024-2.
(6). Huang YY, Jiang CQ, Zhang WS(*), Zhu F, Jin YL, Cheng KK, Lam TH, Xu L(*) Mortality related to changes in physical activity in middle-aged to older Chinese: an 8-year follow-up of the Guangzhou Biobank Cohort Study. Journal of Sport and Health Science. 2021 Jul 1;10(4):430-8.
(7). Cai Q (#), Chen F (#), Wang T, Luo F, Liu X, Wu Q, He Q, Wang Z, Liu Y, Liu L, Chen J(*) and Xu L(*). Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China. Diabetes Care. 2020;43:1392-1398. [Highly Cited Papers]
(8). Cai Q (#), Huang D (#), Yu H, Zhu Z, Xia Z, Su Y, Li Z, Zhou G, Gou J, Qu J, Sun Y, Liu Y, He Q, Chen J(*), Liu L(*) and Xu L(*). COVID-19: Abnormal liver function tests. Journal of Hepatology. 2020;73:566-74. [Highly Cited Papers]
(9). Wang XJ, Jiang CQ(*), Zhang WS, Zhu F, Jin YL, Woo J, Cheng KK, Lam TH(*), Xu L(*). Milk consumption and risk of mortality from all-cause, cardiovascular disease and cancer in older people. Clinical Nutrition. 2020;39:3442-51.
(10). Jiang CQ, Xu L(*), Lam TH(*), Jin YL, Sen Zhang W, Zhu F, Thomas GN and Cheng KK. Glycaemic measures and risk of mortality in older Chinese: the Guangzhou Biobank Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 2019; 105(3): e181–190. doi: 10.1210/clinem/dgz173.
(11). Ma XQ, Jiang CQ(*), Xu L(*), Zhang WS, Zhu F, Jin YL, Thomas GN and Lam TH. Sleep quality and cognitive impairment in older Chinese: Guangzhou Biobank Cohort Study. Age Ageing. 2019;49(1):119-124. doi: 10.1093/ageing/afz120.
(12). Xu L, Borges MC, Hemani G, Lawlor DA. The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study. Diabetologia. 2017;60(11):2210-2220.
(13). Xu L, Jiang CQ, Lam TH, Zhang WS, Zhu F, Jin YL, Thomas GN, Cheng KK and Schooling CM. Mendelian randomization estimates of alanine aminotransferase with cardiovascular disease: Guangzhou Biobank Cohort study. Hum Mol Genet. 2017;26:430-437.
(14). Xu L, Lam TH, Jiang CQ., Zhang WS, Jin YL, Zhu T, Thomas GN, Cheng KK. Changes in adiposity in an older Chinese population in rapid economic transition. Obesity, 2016;24(10), 2217-2223.
(15). Lam TH(#), Xu L(#), Schooling CM(*), Chan WM, Lee SY, Leung GM. Smoking and mortality in a prospective cohort study of older chinese in Hong Kong. Addiction. 2015;110(3):502-510.
(16). Xu L, Jiang CQ, Lam TH(*), Zhang WS, Cherny SS, Thomas GN, Cheng KK. Sleep duration and memory in the elderly chinese: Longitudinal analysis of the Guangzhou Biobank Cohort Study. Sleep. 2014;37:1737-1744
(17). Xu L, Freeman G, Cowling BJ, Schooling CM(*). Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials. BMC Medicine. 2013;11:108. [Highly Cited Papers]
(18). Xu L, Schooling CM(*), Chan WM, Lee SY, Leung GM, Lam TH. Smoking and hemorrhagic stroke mortality in a prospective cohort study of older Chinese. Stroke. 2013;44(8):2144-2149.
(19). Xu L, Jiang CQ, Lam TH(*), Liu B, Jin YL, Zhu T, Zhang WS, Cheng KK and Thomas GN. Short or long sleep duration is associated with memory impairment in older Chinese: the Guangzhou Biobank Cohort Study. Sleep 2011;34(5):575-80.
(20). Xu L, Jiang CQ, Lam TH(*), Cheng KK, Yue XJ, Lin JM, Zhang WS and Thomas GN. Impact of impaired fasting glucose and impaired glucose tolerance on arterial stiffness in an older Chinese population: the Guangzhou Biobank Cohort Study-CVD. Metabolism 2010;59(3):367-72.
(21). Xu L, Jiang CQ, Lam TH(*), Yue XJ, Cheng KK, Liu B, Jin YL, Zhang WS and Thomas GN. Brachial-ankle pulse wave velocity and cardiovascular risk factors in the non-diabetic and newly diagnosed diabetic Chinese: Guangzhou Biobank Cohort Study-CVD. Diabetes Metabolism Research & Review 2010;26(2):133-9.
五、研究生培养情况: 自2012年以来平均每年培养3-6名硕士研究生,自2015年以来担任香港大学博士生联合导师,2016年以来担任中山大学博士生导师,2020年以来担任英国伯明翰大学研究生联合导师
六、招生专业: 慢性病流行病学
七、获奖情况
2008 获贺达理教授奖(Professor Anthony Hedley Prize for Master of Public Health), 香港大学(年级总分第一名,优秀毕业论文奖)2011获龍榮軾教授及朱淑濂女士研究生奖学金(YS and Christabel Lung Postgraduate Scholarship), 香港大学2011年参与项目《广州生物库中老年队列的建立与常见慢性重大疾病的相关因素研究》,研究团队获中华预防医学会科学进步奖二等奖2012再次获龍榮軾教授及朱淑濂女士研究生奖学金(YS and Christabel Lung Postgraduate Scholarship), 香港大学2014年参与项目《广州生物库中老年队列的建立与常见慢性重大疾病的相关因素研究》,研究团队获广东省科学技术进步奖二等奖2015年获香港大学/美国中华医学基金会(University of Hong Kong/China Medical Board)联合基金资助网址:徐琳 https://mxgxt.com/news/view/195382
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